Detailed Drug Information:
DRUG CLASS AND MECHANISM: Potassium chloride is in the class ofdrugs called potassium supplements which are used to treat low potassiumconditions (hypokalemia) or prevent them from occurring. Potassium is theprincipal positive ion inside of the cells of the body and is used innerve conduction, muscle contraction, and normal kidney function. Adeficiency of potassium causes weakness, fatigue, heart rhythm problems,paralysis, and kidney dysfunction.
PREPARATIONS: Tablets and capsules; 8 mEq, 10 mEq, 20mEq.Slow-K 8 mEq extended-release tablets; Powder and liquid also available.
STORAGE: Potassium should be stored at room temperature in atight container.
PRESCRIBED FOR: Low potassium conditions (hypokalemia) occurwhen the amount of potassium lost in the kidneys or intestines exceeds theamount of potassium taken in. This usually occurs slowly with the use ofdiuretics. However, it can also occur in diabetic ketoacidosis, severediarrhea, conditions wherein the patient is receiving IV fluids and noteating, and rare disorders of the adrenal glands. Potassium chloride isused to treat hypokalemia and to prevent hypokalemia from occurring whenstrong diuretics are used. Potassium can also be used to treat digitalistoxicity.
DOSING: Potassium is usually taken with meals and fluids toprevent intestinal problems.
DRUG INTERACTIONS: Cardiac arrest can occur with high potassiumconditions, such as chronic renal failure, burns, acidosis, dehydration,and potassium sparing diuretic usage. Potassium supplements should not begiven to these patients. Ulcers and bleeding can occur in patients withintestinal problems, especially those who are taking slow-release tablets.Drug interactions causing elevation of potassium can occur with ACEinhibitors (used to treat high blood pressure) and certain diuretics(aldactone and triamterene). Blood tests to measure potassium levelsshould be followed regularly in these patients. Slow-release tabletsshould be swallowed, not chewed or crushed.
SIDE EFFECTS: Severe side effects include high potassium andintestinal bleeding, ulceration, and perforation as mentioned above in DRUG INTERACTIONS. More common reactions include nausea, vomiting,diarrhea, and abdominal pain.
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