Detailed Drug Information:

PREPARATIONS: Ophthalmic solution 0.005%: 2.5ml.

STORAGE: Latanoprost should be kept at room temperature, 15-30°C(59-86°F) and protected for direct light.

PRESCRIBED FOR: Latanoprost is used for the treatment ofglaucoma.

DOSING: The hands should be washed before each use oflatanoprost or any eye medication. The head is tilted back and the lowereyelid is pulled down with the index finger to form a pouch. (It isimportant not to touch the tip of the dropper to the eye or the eyelid sothat bacteria are not introduced into the bottle.) The bottle is squeezedslightly to allow the prescribed number of drops into the pouch. The eyethen is closed gently for 2 to 3 minutes without blinking. The usual doseis one drop into the affected eye once daily.

DRUG INTERACTIONS: No drug interactions have been describedwith latanoprost eye drops.

PREGNANCY: Although no human studies have assessed the effectsof latanoprost on the fetus, animal studies have shown damage to thefetus. Physicians should use latanoprost during pregnancy only if itsbenefits are deemed to outweigh the potential risks to the fetus.

NURSING MOTHERS: It is not known if latanoprost is secreted into breast milk.

SIDE EFFECTS: Between 5% and 15% (between 1 in 20 and 1 in 6)of persons receiving latanoprost for 6 months report at least one sideeffect localized to the eyes. These side effects included blurred vision,redness, a sensation of a foreign body, discoloration of the iris,itching, burning, and stinging. Discoloration of the iris begins happensslowly. It is caused by an increase in the amount of brown pigment in theiris and may be permanent. Other side effects which have been reportedless frequently include dryness of the eyes, increased tearing, eye painand other eye-related discomfort.